For the first time, scientists have made a molecular motor from lignin-containing hardwood.
Lignin is a natural polymer and a key component of plant cell walls. It is also the largest renewable source of aromatic chemicals. Although lignin depolymerisation strategies have been used to produce various aromatic platform chemicals, converting lignin into high-value molecules with specific functions, such as molecular motors, is underexplored.
In 2018, a team surroundingKatalin Barta, from the University of Graz in Austria, reported a reductive catalytic fractionation strategy that combined biomass fractionation and lignin depolymerisation to produce dihydroconiferyl alcohol and dihydrosinapyl alcohol from softwood and hardwood, respectively. The method used a copper-doped porous metal oxide (Cu20PMO)催化剂,使得reta的化学物质in their primary alcohols. This functionality is important for further conversion to indanones, which can serve as building blocks for molecular motors and switches.
Now, Barta has teamed up withBen Feringaat the University of Groningen to prepare a light-driven unidirectional molecular motor (see interactive structure below) in six environmentally benign steps from lignin-derived dihydrosynapyl alcohol. Using a modular synthetic strategy based on the principles of green chemistry, they showed for the first time that such a highly sophisticated functional molecule can be made from entirely renewable resources.
Molecular motors and switches have already found application in drug delivery systems, responsive coatings and muscles for soft robotics. This proof-of-concept work identifies a general strategy for making such high-value functional molecules from sustainable feedstocks.
References
1 T Freeseet al,绿色化学。, 2022, DOI:10.1039/d2gc00291d
2 Z Sunet al,Nat. Catal., 2018,1, 82 (10.1038/s41929-017-0007-z)
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